This episode features rheumatologist Bill Giannakopoulos discussing his unified theory connecting consciousness, disease, and AI. Topics include reversible computation's role in memory and healing, mutual information in biology and society, AI agents in scientific inquiry, and creating coherence in human-artificial systems—spanning medicine, information theory, and consciousness.

Federico Faggin is best known as the inventor of the first commercial microprocessor — but his journey didn’t stop with silicon. In this mind-expanding episode, he explores the science of consciousness, the nature of free will, and what reality really is. With deep insight into quantum physics and decades of philosophical exploration, Federico reveals why consciousness isn’t just a brain function — it’s the foundation of everything.

In this episode, I sit down with Will Ratcliff, a full professor at Georgia Tech and director of the interdisciplinary graduate program in Quantitative Biosciences, to explore the evolutionary secrets of cooperation, complexity, and stability. Will’s research focuses on how multicellular life evolved and what biology can teach us about building stable, adaptive systems—whether in AI, governance, or economics.

Michael Levin dives deep into the intersection of biology and artificial intelligence, exploring how individual units—whether cells or humans—can form cohesive, goal-driven systems. Sharing insights into "cognitive glue," the mechanisms that bind entities into intelligent collectives, and how these principles apply to designing ethical AI. We also tackle the challenge of misinformation, the fluidity of memory and understanding, and the potential dangers and promises of AI-driven societal structures.

Renowned neuroscientist Stuart Hameroff explores the groundbreaking concept of quantum consciousness, proposing that microtubules, quantum coherence, and aromatic rings play a key role in consciousness. Combining physics, biology, and neuroscience, he challenges traditional brain theories and examines implications for AI, spirituality, and quantum computing.

In this episode, we delve into the fundamental questions surrounding intelligence, consciousness, and the underlying science. We explore insights on the future of artificial intelligence, the importance of neuroimaging, and the potential for new treatments for neurological and psychological disorders. Discover the fascinating intersection of mind, brain, and behavior.

In this episode, we explore the challenges and opportunities of building sophisticated models with active inference, focusing on practical implementation in scalable AI and the future of principled AI in solving real-world problems.

In this episode, we discuss the nature of consciousness with Professor Anil Seth, a leading cognitive neuroscientist at the University of Sussex and author of the bestselling book Being You: A New Science of Consciousness.

Dr. Karl Friston is a leading neuroscientist and professor at University College London. Dr. Friston is renowned for his work on the free energy principle and active inference, which have profound implications for our understanding of the brain, artificial intelligence, and the nature of consciousness.

Popular science author, Don Hoffman, is a professor in the Department of Cognitive Sciences at the University of California, Irvine. He leads us into the intriguing intersection of evolution, perception, and intelligence.

In this episode, Dr. Fields discusses the free energy principle, active inference, and the implications of these concepts for understanding intelligence and life. Discover how systems interact with their environments, the role of internal degrees of freedom, and the profound impact of these ideas on science and technology.